In my case the problem was that a blank tab was opening along with the home page, but it could be a website, search engine, ad page and so on. The cause is always the same and it is usually quite easy to solve.
Here is a pic of the problem on my PC. There is an about:blank tab:
The cause is either in Chrome's settings or extensions. It could be in both. Enter chrome://extensions in the address box and take a close look at each one. Are you sure that you need them all? Are there any that you don't remember adding? One of them could be the cause of the extra tab, so disable them all, close Chrome and restart it. If it starts up OK then you will know that the cause is one of the extensions you disabled.
In my case this did not help. If it is not an extension, the problem is in the settings. Go to the menu and select Settings.
Go to the On startup section and it will be set to Open a specific page or set of pages. Click the Set pages link. This is what was on my PC:
Any number of pages can be set here and each one will be opened in its own tab when Chrome is started. If there is more than one entry, then that is your problem and the unwanted tab or tabs must be deleted.
In my case, only one home page is specified, so where was the about:blank tab coming from? I must admit that it had me fooled for several minutes and it was only when I accidentally moved the mouse over this that I saw the problem.
There is in fact, an extra entry, but it is blank. That is why it was opening about:blank in the other tab on startup. The way to remove unwanted startup pages is to mouse over them and then click the cross at the right side. When this was done, Chrome only started up with the specified home page.
It is common for free software downloads to included unwanted extras, PUPs or potentially unwanted programs. These often add extra startup pages and may include an extension. Deleted the extension, remove the startup page and Chrome will be returned to normal.